Ensure that the pubs and clubs you intend to visit are relatively close to your accommodation - trekking through the mountains all night can get tiring, and cold.
The altitude of the resort will effect the speed at which alcohol hits. Bear in mind that you'll body will not be able to handle as many drinks in resort as it would at home
Make sure your budget can handle your nightlife - Alpine prices can be as steep as the mountains themselves.
Don't let tonight ruin tomorrow if you've paid for tomorrow's skiing - you can always large it up at home.
Check out when and where the various happy hours are - and make it a happy night.
Don't drink and slide - your insurance will be invalid if you have an accident while being under the influence!